Moderna faces challenges with respiratory vaccine sales and strong competition. Click here to read an analysis of MRNA stock ...

Gain expert insights in this interview on achieving transfection success. Explore proven strategies to optimize your approach ...

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Researchers from the International Institute of Molecular and Cell Biology in Warsaw (IIMCB) have described a new mechanism ...

However, mRNA itself is an exceptionally unstable molecule. This does not affect the safety of the therapy but limits its effectiveness—for example, by shortening the duration of action. A ...

Because RNAs are so central to our biology, they are also drivers of a wide array of diseases. Defects in how RNA is produced and processed can lead to cancer, degenerative diseases, metabolic ...

The identification and intervention of Alzheimer's Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of ...

In the default model, the graph representing each individual enhancer can be arbitrarily complicated. To show how the ABC Score formula can arise from the default model, we need to impose the further ...

Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of ...

The surprise delay is casting new uncertainty on the fate of another vaccine awaiting FDA action: Moderna’s next-generation Covid-19 shot, called mRNA-1283, which is set for a decision by May 31.

Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA splicing. Two molecular control factors play a key role in splicing, the process ...