This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

CRISPR epigenome editing successfully reactivates silenced genes in Prader-Willi Syndrome, highlighting potential for ...

Advanced diagnostic techniques, such as genetic testing, enzyme assays, and imaging technologies like MRI and ... These therapies are focused on enhancing the activity of enzymes or replacing missing ...

Skatole is an infamously smelly molecule that, in some anaerobic bacteria, is synthesized from ʟ-tryptophan in a four-step ...

Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) and antioxidant defenses, plays a central role ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

When a tumour develops, it creates a structure around itself called the tumour stroma, within which blood and lymphatic vessels ensure nutritional and respiratory biological exchanges.

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with ...

The study developed a noninvasive detection method based on serum protease activity, leveraging the increased protease activity in the peripheral blood of patients with PDAC. Researchers screened a ...