Imagine the magnificent glaciers of Greenland, the eternal snow of the Tibetan high mountains, and the permanently ice-cold ...

Master the art of identifying small molecules through mass spectrometry. Join our course for hands-on training in data ...

Rational drug design depends on the knowledge of the three-dimensional (3D) structure of complexes between proteins and lead compounds of low molecular weight. A novel nuclear magnetic resonance (NMR) ...

Essentially, cereblon and its target proteins can change shape to form a complex with the cereblon, the target, and the ...

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

Single particle, cryogenic electron microscopy (cryoEM) experiments now routinely produce high-resolution data for large proteins and their complexes. Building an atomic model into a cryo-EM density ...

Machine learning methods are widely used in bioinformatics and computational and systems biology. Here, we review the development of machine learning methods for protein structure prediction, one of ...

Using the Experimentally Determined Components of the Overall Rotational Diffusion Tensor To Restrain Molecular Shape and Size in NMR Structure Determination of Globular Proteins and Protein−Protein ...