Although darbepoetin alfa can effectively increase hemoglobin levels, its effect on clinical outcomes in these patients has not been adequately tested. Death or a cardiovascular event occurred in ...

All patients were scheduled to receive darbepoetin alfa (Aranesp; Amgen, Thousand Oaks, CA) 500 μg subcutaneously every 3 weeks until Hb reached greater than 11.0 g/dL and thereafter to receive ...

We evaluated the effects of darbepoetin alfa on clinical outcomes in patients with systolic heart failure and anemia. The primary outcome occurred in 576 of 1136 patients (50.7%) in the ...

Darbepoetin alfa is the recombinant product of a gene produced through site-directed mutagenesis of the erythropoietin gene that increases the glycosylation of the protein. Darbepoetin alfa binds ...

Patients had a diagnosis of nonmyeloid malignancy with ≥ 8 weeks of planned chemotherapy, age ≥ 18 years, and anemia (hemoglobin ≤ 11 g/dL). Patients were randomly assigned 1:1 to DA 200 μg every two ...

Erythropoiesis-stimulating agents (ESAs), such as epoetin alfa or darbepoetin alfa, are recommended in clinical guidelines to treat anemia in patients with lower-risk MDS, who generally have low ...

Patient characteristics are summarized in Table 1 . A total of 14 patients received at least one dose of darbepoetin alfa, and the 12 who received more than one dose were assessable. Eleven ...

Nephrol Dial Transplant. 2006;21:2846-2850 Darbepoetin alfa administered once every two weeks (Q2W) safely and effectively treats anemia in hemodialysis patients without having to increase the ...

Vadadustat appeared to have similar efficacy to darbepoetin alfa with a least square mean difference in Hb of -0.01 g/dL. Mean Hb at 24 to 36 weeks was 10.77 vs 10.77g/dL, respectively.

Mean baseline Hb levels were 10.77 g/dL for molidustat and 10.84 g/dL for darbepoetin alfa. Over a median 364 days, mean Hb was maintained at 10.63 g/dL with molidustat compared with 10.77 g/dL ...

Purpose: The cost of darbepoetin alfa versus that of epoetin alfa in a hospital setting was studied. Methods: The study was an observational, retrospective review of the hospitalwide use of ...

Find out how to take Darbepoetin Alfa (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed. We recommend consulting your doctor to verify ...