It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon ...

Cancer is cruel. It doesn’t care that you’re only 37, that you're the mother of a little girl who is your entire world. So Elissa vowed to fight.

Thetis cells, a class of immune cells first described in 2022, play an essential and previously unknown role in suppressing inflammatory responses to food, a new study finds.

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes ...

CytomX's CX-2051, a PROBODY® EpCAM-targeted antibody-drug conjugate (ADC), showed a 28% confirmed response rate and 5.8-month ...

Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes ...

Gut organoids mimic the stomach, small intestine, and colon in 3D. Learn how these lab-grown models are advancing digestive ...

Human IEOs from ileum and colon show a stable highly gut segment-specific epigenetic ... Dividing adult stem cells located at the crypt base give rise to all major epithelial cell lineages and enable ...

Objective Colorectal tumours are often densely infiltrated by immune cells that have a role in surveillance and modulation of tumour progression but are burdened by immunosuppressive signals, which ...

colorectal cancer (CRC). “These data show how TP-317 can meaningfully impact immune-mediated diseases by activating the BLT1 pathway. In IBD, TP-317 promotes epithelial repair and resolves ...

Department of Biology, College of Science, Shantou University, Shantou 515063, Guangdong, China Guangdong Provincial Key Laboratory of Marine Biotechnology, Institute of Marine Sciences, Shantou ...

can directly damage the DNA of colorectal epithelial cells, inducing gene mutations; on the other hand, smoking can also impair immune function, weakening the body’s immune surveillance and clearance ...