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The identification of promising lead compounds from high-throughput screens is still a very complex problem. A new high-throughput assay for identifying aggregation-based false positives could help.
What can you learn from a tree's leaves? Discover how leaf shapes, edges, patterns, and more can help you identify a tree in the forest.
Thiol-reactive compounds, byproducts of wastewater chlorination, are under scrutiny for their high potential toxicity in water reuse applications. To date, a limited number of compounds have been ...
We describe a semiautomated and microplate-based parallel compound library approach leading to the rapid discovery of celastrol derivatives that are potent and selective PRDX1 inhibitors.