High nuclear accumulation of NONO-TFE3 or PRCC-TFE3 fusion proteins promotes their broad binding across the genome at H3K27ac-marked active chromatin ... in cell proliferation (regulation of cell ...

Cell cycle-related kinase (CCRK ... Design Transcriptional regulation was assessed by chromatin immunoprecipitation, promoter mutation and luciferase reporter assays. Hepatocellular proliferation and ...

Since 2014, she leads her own research team in Weill Cornell Medicine in New York studying the critical interplay between TFs, 3D chromatin organization and transcription during cell cycle or cell ...

cycle (2). As a result, lactate accumulates within tumor cells, indicating the need for efficient export mechanisms to prevent intracellular acidification and maintain metabolic homeostasis. Given its ...

Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

Breast cancer is becoming increasingly treatable, but in some cases the disease can resurface even decades after a patient ...

Menstrual Cycle Could Be Contributing To Sickle Cell Pain Events By Dennis Thompson HealthDay Reporter MONDAY, April 14, 2025 (HealthDay News) -- Women with sickle cell disease often have pain ...