Signal transducer and activator of transcription 6 (STAT6) is a member of the STAT family involved in the regulation of immune response and inflammation. The development of SH2 domain inhibitors ...

Last week, Gilead Sciences, Inc. GILD reported better-than-expected fourth-quarter results. Adjusted earnings per share (EPS) of $1.90 beat the Zacks Consensus Estimate of $1.67. In the year-ago ...

Activation of an immune signaling molecule called STAT6 may lead to pulmonary hypertension (PH) in people with oxygen deprivation due to obstructive sleep apnea, according to a recent study in mice.

Anterior gradient 2 (AGR2) is a protein located in the endoplasmic reticulum involved in protein folding and when stressed, it is secreted into the extracellular space and it attracts monocytes, ...

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We aimed to define the impact of VD on oesophageal allergic inflammation. Design We assessed the genomic distribution and function of VD receptor (VDR) and STAT6 using histology, molecular imaging, ...

KT-621 (STAT6) Phase 1 healthy volunteer trial ongoing, complete SAD/MAD data expected in June 2025 KT-621 Phase 1b trial in atopic dermatitis (AD) patients expected to initiate in 2Q25 with data in ...