A protein called BMPER found at low levels in models has emerged as a PAH treatment target as it may ease disease progression ...

All diseases exist on a continuum, and the damage often begins early—sometimes as soon as a child is weaned off breast milk and starts consuming regular table food. In a previous blog, I discussed ...

Single-cell RNA sequencing confirmed vascular heterogeneity and revealed that timing the expression of transcription factors enabled modulation of angiogenic and arterial endothelial phenotypes.

Marijuana smokers had lower NO levels in the endothelial cells compared to non-users, suggesting that regular marijuana use could impair endothelial function and blood vessel health.

Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC ...

Patients with predominantly cranial vs isolated extracranial GCA phenotypes present with different patterns of arterial involvement on 18F-FDG PET-CT scans.

Endothelial cell dysfunction, in its broadest sense, encompasses a constellation of various nonadaptive alterations in functional phenotype, which have important implications for the regulation of ...

We found that mature pial collaterals are mostly derived from an embryonic arterial lineage (87%) and, to a lesser degree, from an embryonic microvascular lineage (23%). We provide evidence for mosaic ...

Collateral arteries act as natural bypasses which reroute blood flow to ischemic regions and facilitate tissue regeneration. In an injured heart, neonatal artery endothelial cells orchestrate a ...

Spatio-temporal analysis using live imaging in zebrafish reveals mural cells as a source of pro-lymphangiogenic factors including chemokine and growth factor signalling, necessary for robust lymphatic ...