A phase 2 trial found that adding bevacizumab to alectinib significantly delayed disease progression, protected against brain ...

Neurons deep in the brain not only help to initiate movement—they also actively suppress it, and with astonishing precision. This is the conclusion of a new study by researchers at the University of ...

Under terms of the deal, Pfizer will gain rights to develop, manufacture, and commercialize SSGJ-707 outside of China.

A Detailed Global Outlook to 2035Allergy immunotherapy, a transformative solution in modern medicine, is revolutionizing ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system ...

To explore the role of Nrf2 in OB differentiation and whether NAR affects osteogenic differentiation through the Nrf2/HO-1 signaling pathway, NAR and ML385 were used to treat the OBs. Figure 8D–G ...

The sustained selective pressure of the drug leads to resistance-promoting changes in the ALK protein itself, but also changes in other cell signaling pathways can lead to insensitivity to ALK ...

Here, we identify an underlying molecular mechanism, in which ALK signaling leads to phosphorylation of ATR ... Given that targeting of the DDR leads to activation of the cGAS-STING pathway, we also ...

In a study of mice, researchers worked out a neural pathway that could help researchers ... of a mystery how the brain gets the alarm signal, then sends another one to tell the stomach to initiate ...