The paper is titled "Dietary pyruvate targets cytosolic phospholipase A2 to mitigate inflammation and obesity in mice." Pyruvate, a glycolytic metabolite, was found to inhibit adipogenic ...

This paper describes the Tmod dual-targeting system ... normal cells and accessing new cancer targets. A2 plans to use Tmod to exploit the large, untapped source of targets that are lost in ...

A major hurdle for using engineered CAR-T cells to treat solid tumors is the lack of tumor-specific markers for therapies to target ... normal cells, A2 Bio reported in a paper published in ...