United Airlines flight 4166 — from Pennsylvania to Chicago — made an emergency descent after rapidly losing cabin pressure 40,000 feet above Ohio.

The plane left the Lehigh Valley International Airport in Allentown, Pennsylvania, around 5:24 a.m. and was expected to arrive at Chicago's O'Hare International Airport at 8:44 a.m.

United predicted first-quarter profit well ahead of Wall Street’s estimates as the carrier capitalizes on unusually strong demand for premium and international travel.

The Federal Aviation Administration is once again looking into a close call at a major U.S. airport, after two passenger jets narrowly avoided a mid-air collision as they attempted to land in Phoenix.

A United Airlines flight Sunday from Lehigh Valley International Airport to Chicago was diverted to Detroit because of a possible problem with the cabin pressure.

American Airlines Group Inc. tumbled after forecasting a surprise first-quarter loss in a setback as the carrier works to win back corporate travel after a strategic blunder last year.

The United Airlines flight was forced into a sharp fall after experiencing a sudden fault at 40,000ft prompting an urgent call to air traffic control

Winter weather forced the closure of Houston's two main airports, causing numerous flight cancellations, primarily impacting United Airlines and Southwest Airlines. Houston's two main airports remained closed for winter weather on Tuesday, leading to hundreds of canceled flights.