BACKGROUND: Vascular aging is an important phenotype characterized by structural and geometric remodeling. Some individuals ...

The era of predictive modeling enhanced with machine learning and artificial intelligence (AI) to aid clinical ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Cardiovascular disease (CVD) mortality increased by 78%, rising from 72.4 to 128.7 per 100 000 (2017–2022), with the greatest ...

BACKGROUND: Primary aldosteronism (PA), an overt form of renin-independent aldosterone production, leads to a disproportionately high rate of major adverse cardiovascular events (MACEs). Mounting ...

BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

The role of the American Heart Association Journal Health and Longevity Editorial Board is to facilitate more and better science regarding social drivers of health and increase representation of many ...

A 66-year-old woman presented to the clinic with complaints of New York Heart Association Class II exertional dyspnea and easy fatiguability for 3 months. General physical and cardiac examination were ...

Background: Urinary thromboxane B2 metabolites (TXB2) are biomarkers of systemic thromboxane A2 (TXA2) activity, an eicosanoid synthesized from arachidonic acid (AA) that is recognized to contribute ...

Despite decades of technique refinement of transarterial embolization and the establishment of specialty referral centers, fetuses diagnosed with vein of Galen malformation continue to have high ...

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports on the most up-to-date statistics related to heart disease, stroke, and ...

Gene Ontology analysis from differentially expressed genes revealed expected changes in cell cycle, metabolism, and contractility. In addition, mRNA splicing was among the top enriched differentially ...