In 1994, a panel appointed by the Stroke Council of the American Heart Association authored guidelines for the management of patients with acute ischemic stroke. 1 After the approval of the use of ...

Stroke is the third-leading cause of death in the United States and a leading cause of disability. Its manifestations are extremely variable and often profoundly and permanently change a patient's ...

Cis‐expression quantitative trait loci data for druggable genes were used as instrumental variables. The primary outcome was the modified Rankin Scale score at 3 months after ischemic stroke, ...

Blood pressure (BP) level is determined by just 2 variables: peripheral vascular resistance and cardiac output, but it exhibits a Gaussian distribution in the general population indicating that it is ...

In contrast to coronary artery disease, heart failure, valvular disease, and other topics in the field of cardiology, there are few data from randomized trials to guide physicians in the management of ...

The energy starvation hypothesis suggesting that the failing heart is energy-starved is decades old. 1,2 Because ATP is required for normal systolic and diastolic contractile performance, the idea ...

The development of high blood pressure is influenced by genetic and environmental factors, with high salt intake being a known environmental contributor. Humans display a spectrum of ...

Prevalence of Asymptomatic CHD in Patients With TIA or Stroke Several small studies have shown that patients with TIA and stroke have a high prevalence of asymptomatic CHD. 6–8 Rokey et al 6 performed ...

Background and Purpose— Prompt recognition of stroke symptoms is critical to timely treatment and women have increased delay to treatment. Women may be more likely to present with atypical symptoms, ...

Abstract In this review, we outline the current knowledge on the regulation of nitric oxide (NO)-sensitive guanylyl cyclase (GC). Besides NO, the physiological activator that binds to the prosthetic ...

Previous cost-effectiveness models found ambulatory blood pressure monitoring (ABPM) to be a favorable strategy to diagnose hypertension; however, they mostly focused on older adults with a positive ...

Stroke is a common and serious disorder, with an incidence of ≈795 000 each year in the United States alone. Worldwide, stroke is a leading cause of death and disability. Recombinant tissue ...