The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions of life. Inside each cell, catalysts seek out the appropriate information from ...

During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together of amino acids—the building blocks of proteins. As the translation ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

Cells express their genes by converting the genetic message into protein. This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients ...

Hidden within the genetic code lies the "triplet code," a series of three nucleotides that determine a single amino acid. How did scientists discover and unlock this amino acid code? Once the ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA—a prerequisite for protein synthesis in the cell. The poorly ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

For as long as living things have been building proteins based on the code carried by messenger RNA molecules, aminoacyl-tRNA synthetases have been there. These enzymes, AARSs for short, link transfer ...

Starting points for the control of protein synthesis Date: March 20, 2025 Source: Universitatsklinikum Bonn Summary: The research field of 'cellular IRESes' lay dormant for decades, as there was ...