The python's head was as big as a garden spade, lunging at hunter once, twice, before sinking its recurved teeth into his arm.

As the Florida Python Challenge gets closer, let's take a look at the largest Burmese pythons caught in Florida.

Researcher Ian Bartoszek sifts through dozens of proto-eggs while performing a necropsy on the largest female Burmese python ever discovered in Florida.

Residents in Prosperity, S.C., are sleeping peacefully now that a monstrous python on the loose has been captured.

Researchers captured the biggest Burmese python on record in Florida this spring: a 215-pound female containing 122 developing eggs.

An 18-foot python is now the second largest python ever caught in the wild in Florida.

An exclusive, behind-the-scenes look at the quest to rid the Everglades of invasive Burmese pythons—including a record-breaking, 215-pound giant.