Now that the San Francisco 49ers schedule is here, what better time than to predict the outcome of every single game? It’s impossible to project what will happen between now and January. We thought the 49ers would go 12-5 when we did this exercise last season.

The San Francisco 49ers' defense struggled against the run in 2024, allowing 124.6 rushing yards per game under defensive coordinator Nick Sorensen, ranking 18th in the NFL.

In San Francisco, Boyer takes over a unit that finished last in the league in special teams EPA (negative-47.67) last season, which was nearly 24 points worse than the next-closest team (the Atlanta Falcons ). Since 2016, the 49ers are 27th in the NFL in cumulative special teams EPA.

Fortunately, the 49ers were one of the big winners of the NFL's schedule release according to CBS Sports.

Panthers HC Dave Canales on actually having a primetime game on the schedule: "Those are the types of games that we need to become who we are."

The San Francisco 49ers made a handful of mistakes during the 2025 NFL Draft. Will it cost them during the 2025 season?

The San Francisco 49ers could continue their emphasis on replenishing the defense by signing one of the best young free agents available.