Advise patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended. Fluorouracil interferes with the synthesis of deoxyribonucleic acid (DNA) and to a lesser ...
The severity of skin reactions to the treatment of actinic keratosis with 5-fluorouracil cream 4% was associated with a higher lesion clearance rate.
A database search of PubMed and Embase was performed from 1965 to April 2012 using the terms 'actinic keratoses', 'solar keratoses', 'topical 5-fluorouracil', 'topical 5-FU', 'double-blind ...