Journal clubs, typically involving a group of health professionals or trainees who discuss recent study findings, have long ...

MetaImpact. To design a new trial based on the prospective updated meta-analysis, Sutton et al5 propose a hybrid frequentist–Bayesian approach using simulations. New studies of a user-defined size are ...

Understanding the causes of deaths and how they can be prevented is critical for improving healthcare outcomes. At a population level, over-reporting or under-reporting of deaths can have a profound ...

Introduction. The concepts of evidence-based medicine are evolving as limitations of early models are addressed. In this editorial, we present a new model for evidence-based clinical decision making ...

Computational methods can contribute to evidence management with automation of literature searching, critical appraisal and guidelines.4 5 Similarly, big data already contribute to aetiological, ...

Objectives To describe the proportion of transvaginal ultrasounds performed in a University Hospital of Buenos Aires (Argentina), requested upon a health check. Method Cross-sectional study of a ...

The effects of statins in the elderly are better informed by absolute effects and the number needed to evaluate the benefit to harm balance. Such an approach enables patients to make more informative ...

Commentary on: Callen JL, Westbrook JI, Georgiou A, et al. Failure to follow-up test results for ambulatory patients: a systematic review. J Gen Intern Med 2012; 27: 1334– 48.[OpenUrl][1][CrossRef][2] ...

This article is part of a series of articles featuring the Catalogue of Bias introduced in this volume of BMJ Evidence-Based Medicine that describes attrition bias and outlines its potential impact on ...

Evidence synthesis is a key element of evidence-based medicine. However, it is currently hampered by being labour intensive meaning that many trials are not incorporated into robust evidence syntheses ...

Introduction Digital medical devices (e.g., continuous glucose monitors), healthcare apps, and electronic health record tools like patient portals have significantly altered patient self-management ...