mRNA splicing is a fundamental part of the process that occurs when encoded DNA instructions are turned into a functional protein. After a gene is transcribed from DNA to RNA, extraneous sections ...

How can only 25,000-30,000 protein-coding genes in humans produce the massive variety of proteins, cells, and tissues that exist in our bodies? The answer: alternative splicing. A critical finding ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms. Next, the snRNPs U2 and U4/U6 appear to ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

The New York-based public benefit corporation is advancing three drug candidates for the extremely rare condition.

Researchers suggest discovery of genetic link between ASD and DM1 opens up potential new therapeutic avenues for ASD.

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

Ovarian cancer, a leading cause of death among gynecological malignancies, has a poor prognosis and low 5-year survival rate, necessitating new therapeutic strategies. CDK4/6 inhibitors show promise ...

Get Instant Summarized Text (Gist) Two molecular control factors, GPATCH1 and DHX35, are crucial for ensuring the accuracy of mRNA splicing, a process essential for protein synthesis. These ...

In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases.