The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

US-based biotechnology company Alltrna is developing transfer RNA (tRNA)-based therapies that aim ... gene editing, or mRNA, ...

RNA-based technologies are a powerful molecular biology toolbox, empowering scientists to decipher the complexities of living ...

Messenger RNA (mRNA) carries the genetic information from DNA to the ribosomes, where proteins are synthesized. Transfer RNA (tRNA) and ribosomal RNA (rRNA) are involved in the translation of mRNA ...

The mRNA then travels to the ribosome ... Wobble base pairing enables a single tRNA molecule to recognize multiple codons for the same amino acid, reducing the number of tRNA molecules required for ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

First described in the 1960s, tRNA molecules are cross-shaped nucleotide loops that attach to an amino acid on one arm and recognize a specific mRNA codon with another. Canonically, their sole purpose ...