Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...

By quantifying the number of mRNA transcripts, the ones inside the cell and those bound to ribosomes, the team found that the translation efficiency of the branched mRNA was approximately 1.5 times ...

Follow-up studies confirmed that this nucleoside modification improved mRNA translation capabilities and stability. In the last decade, a series of studies highlighted the powerful potential of ...

The identification and intervention of Alzheimer's Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of ...

They found that mRNA-based COVID-19-vaccinations cause a significant and persistent change through acetylation, i.e., the binding of a chemical group to specific, immunologically relevant genes of ...

Get Instant Summarized Text (Gist) The NIH has reportedly advised scientists to omit mRNA vaccine references from grant applications, suggesting a potential shift away from this research area ...

Wacker Biotech announced a strategic collaboration with RNAV8 Bio, a pioneer in mRNA engineering for the development of ...