The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

A new study has found that messenger RNA can travel between different stem cells and reprogram human cells to an earlier ...

Abe's team overcame this hurdle by introducing a cap structure into the circular mRNA itself. This internal cap structure ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple ...

By quantifying the number of mRNA transcripts, the ones inside the cell and those bound to ribosomes, the team found that the translation efficiency of the branched mRNA was approximately 1.5 times ...

In the course of these studies, we found that 3′UTRs determine where in the cytoplasm an mRNA transcript is translated. Moreover, we found that the cytoplasm is highly compartmentalized into different ...