Customers looking for an mRNA therapeutic partner should prioritize operational excellence and choose flexible CDMOs.

Importantly, this synthesis persisted for an extended period, even after traditional mRNA structures began to degrade. This stability and ability to selectively target cells make Cap-circRNA an ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

The most popular technique for achieving straightforward, scalable, cell-free mRNA synthesis is in vitro transcription-based manufacturing, which consists of the six major processes shown below.

According to the American Cancer Society (2023), in general, about 10–15% of all lung cancers are SCLC, and about 80–85% are ...

RNA cancer vaccines are at the forefront of next-generation cancer immunotherapy, showcasing significant potential.

The inherent instability of mRNA allows cells to rapidly adjust protein levels in response to changing conditions by controlling the synthesis and degradation of specific mRNA molecules. mRNA vaccines ...

2005-2010: Improvements in mRNA synthesis, purification, and stability through chemical modifications and sequence optimization. 2010-2015: Development of lipid nanoparticle delivery systems for ...

Telesis Bio Secures up to $21 Million to Accelerate Adoption of Groundbreaking Gibson SOLA Technology for Rapid DNA and mRNA Synthesis Telesis Bio, a leading provider of DNA and mRNA synthesis ...

With their breakthrough automation solutions for biological synthesis and expertise in DNA biology, they enable DNA and mRNA to be written rapidly, accurately and reproducibly for wide-ranging ...