Researchers develop innovative phospholipids that improve the functional delivery of mRNA via lipid nanoparticles, paving the ...

A new study conducted by researchers at Hokkaido University has unveiled a novel class of zwitterionic phospholipids capable ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the ...

RNA is similar to DNA but contains uracil instead of thymine (T) and has a single-stranded structure. Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

However, in the half-century since the structure of DNA was first elaborated ... Generally, those RNA molecules that do not take the form of mRNA are referred to as noncoding, because they ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

Translation Begins After the Assembly of a Complex Structure The translation of mRNA begins with the formation of a complex on the mRNA (Figure 4). First, three initiation factor proteins (known ...

To answer it, he and his colleagues first used various staining techniques to establish that both RNA-binding proteins and mRNA are colocalized with mitochondria ... throughout the cytoplasm, forming ...

When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA ... adjacent amino acids to finalise the structure.