Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

The R&D Day showcased Everest's proprietary mRNA platform driven by AI and its three leading pipeline assets in cancer and autoimmune disease: the personalized cancer vaccine (PCV) EVM16, the ...

This unique property facilitates membrane fusion-mediated endosomal escape, leading to improved mRNA expression in the liver compared to conventional phospholipids such as DSPC and DOPE. "Endosomal ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

Additionally, mRNA expression lasted up to four weeks -- significantly longer than the typical five-day expression period of LNPs. Notably, ...

In addition, ME Therapeutics is exploring design modifications of its mRNA candidates to modulate mRNA expression in a tissue-specific manner for increased efficacy and safety. About ME Therapeutics.

Researchers are testing the use of mRNA to get damaged livers to repair themselves, in a move that could one day lessen the need for organ transplants.

Two species of worms have retained remarkably similar patterns in the way they switch their genes on and off despite having ...