Therefore, mRNA vaccine design, formulation, and delivery will need to be further improved to compete in this area; and self-amplifying RNAs (saRNA) may become a preferred platform, due to ...

The progression of mRNA-based therapeutics encompasses critical stages such as mRNA design, synthesis, mRNA encapsulation, pharmacodynamics, pharmacokinetics, safety assessments in both in vivo ...

“Over the past four years, Everest has utilized its AI- and big data-powered mRNA platform to accelerate target identification, sequence design and delivery optimization,” Luo continued. “Our ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

As with mRNA COVID vaccines ... send it to the pharmaceutical company, and they design a personalized vaccine that’s bespoke to that patient’s cancer." "That vaccine is not suitable for ...

This acquisition combines Officinae Bio's AI-enabled mRNA design platforms with Maravai and TriLink BioTechnologies' leading drug substance manufacturing capabilities, providing customers ...

Specific DOPE-Cx derivatives, such as DOPE-C8, demonstrated significantly higher mRNA expression levels in the liver ... delivery systems but also opens new avenues for the rational design of ...