Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.

At this point, translation must be terminated, and the nascent protein must be released from the mRNA and ribosome. Termination of Translation There are three termination codons that are employed ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

In this valuable study, Roiuk et al employed a combination of ribosome profiling and reporter assays to provide convincing evidence that eIF2A is not involved in translational regulation in cultured ...

playing a key role in two translation stages: initiation and elongation (helping ribosomes move along the mRNA and add amino acids to the protein chain). Specifically, eIF-5A helps when the ...

Seminal studies that precisely map the production of nascent RNA (Gro-seq) at elongating RNA polymerase II (Net-seq); or RNA in the process of translation (Ribosome-profiling) have revolutionized our ...

The catalytic center of the ribosome, known as the peptidyl transferase center (PTC), is composed entirely of rRNA. The PTC is highly conserved across all domains of life, highlighting the fundamental ...

During protein synthesis, the genetic information stored in DNA is first transcribed into mRNA. The mRNA then travels to the ribosome, where translation occurs. Here's how anticodons facilitate the ...