Based on their experience, Lee's team recommended holding tacrolimus during the 5-day course of nirmatrelvir/ritonavir (or even 1 to 2 days prior to starting the antiviral for high-risk patients ...

The immunosuppressant drug tacrolimus may significantly improve relapse-free survival vs. mycophenolate mofetil for children with frequently relapsing nephrotic syndrome, according to study data.

[20,22,25] Lower tacrolimus disposition in young children might be related to an increased tacrolimus intestinal first pass metabolism resulting from higher CYP3A4 and CYP3A5 expression in the ...

Tacrolimus is available in the form of a capsule, granules for oral suspension (to be mixed with liquid), an extended-release capsule and a tablet to be taken orally.

This paper reviews the currently available evidence on the use of topical tacrolimus in atopic dermatitis and other conditions, as well as its safety profile and cost-effectiveness.

Tacrolimus and cyclosporine A show similar efficacy in long-term survival and relapse reduction in AML post-transplant patients. No significant differences were found in leukemia-free survival ...

To achieve recommended concentrations of tacrolimus in the body, clinicians often prescribe to Black kidney transplant patients higher doses of the drug than white recipients, she explains. Despite ...

Tacrolimus, a calcineurin inhibitor, appears to be an effective alternative to cyclophosphamide for initial treatment of lupus nephritis (LN) of any class, according to new study findings.