Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...
Tacrolimus 0.75mg, 1mg, 4mg; ext-rel tabs. Tacrolimus binds to an intracellular protein, FKBP-12. A complex of tacrolimus-FKBP-12, calcium, calmodulin, and calcineurin (an ubiquitous mammalian ...
Aim: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. Patients & methods: We performed a ...
Omeprazole (as magnesium) 20mg; delayed-release tabs; regular or wildberry flavor. Trouble or pain swallowing food. Vomiting with blood. Bloody or black stools. Chest or shoulder pain with ...