Aim: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. Patients & methods: We performed a ...

The authors suggest that patients who switch to tacrolimus because of failure to reach target C 2 ciclosporin levels should receive a high initial dosage (e.g. 0.25 mg/kg/day) of this ...

Lipella Pharmaceuticals (LIPO) announced the completion of dosing for the first cohort in its multi-center Phase 2a clinical trial of LP-310, a liposomal-tacrolimus oral rinse being developed for ...

Renal impairment, moderate or severe hepatic impairment: monitor and reduce dose if indicated. Obtain tacrolimus whole blood concentrations (see full labeling), serum creatinine, and serum ...

LP-310 Treatment Demonstrates Clinically Meaningful Reductions in Pain, Ulceration, and Inflammation Across All Key Metrics ...

Erythromycin (as base) 333mg, 500mg; del-rel tabs. Erythromycin acts by inhibition of protein synthesis by binding 50S ribosomal subunits of susceptible organisms. It does not affect nucleic acid ...

Lipella Pharmaceuticals Inc. (NASDAQ:LIPO) shared topline an analysis of its Phase 2a dose-ranging trial of LP-310, a ...

Real-time index price for S&P 500 Index (INX), along with buy or sell indicators, analysis, charts, historical performance, ...

Lipella Pharmaceuticals (LIPO) shared topline analysis of its Phase 2a multicenter dose-ranging trial examining LP-310, a liposomal-tacrolimus ...

In the present study, donor CYP3A5 genotype was found to be strongly associated with the time to reach stable tacrolimus therapeutic trough concentrations and tacrolimus daily dose requirements in ...