Heidelberg biochemists and structural biologists from Shanghai unravel the roles of two key regulatory factors in mRNA ...

mRNA splicing is a fundamental part of the process that occurs when encoded DNA instructions are turned into a functional ...

1 Alternative splice sites tend to be suboptimal allowing for modulation by RBPs. At the posttranscriptional level, nonsense mediated decay (NMD) is a process closely linked to alternative splicing ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger RNA – a prerequisite for protein synthesis in the cell. The poorly ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...

A large-scale effort to identify sequences involved in silencing exon and splice site usage sheds some new light on the properties of these poorly understood motifs and demonstrates the potential ...

Similarly, cells splice RNA in different ways to produce a variety of proteins from a single gene, fine-tuning their function based on need. However, when cancer rewrites the script, this process ...

AeroSplice Wire-to-Wire Connecting Solution, a wire splicing system designed to streamline and standardise wire connections in aviation and defence applications. AeroSplice simplifies the often ...