The assembly of a bipolar microtubule-based spindle is crucial for the accurate and timely segregation of the chromosomes into the two daughter cells during mitosis. Three microtubule nucleation ...

a cell type that is simple enough to be understandable and amenable to experimental modification. Recent projects have focused on spindle length instabiliity and self assembly of a bipolar spindle.

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...