Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

The ribosome is a vital cellular machinery responsible for synthesizing proteins by translating messenger RNA (mRNA) sequences into polypeptide chains. This process, known as translation ...

Now the researchers have come closer to understanding how the ribosome works. "It is amazing that we can visualize the atomic details of the ribosome. Because they are tiny—around 20–30 ...

As they are being synthesized, these nascent proteins simultaneously attempt to fold while still associated with their parent ribosome, referred to as co-translational protein folding ...

Although only a few rRNA molecules are present in each ribosome, these molecules make up about half of the ribosomal mass. The remaining mass consists of a number of proteins — nearly 60 in ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...

Prof. Dr. Neva Caliskan Lehrstuhl Biochemie III 93053 Regensburg Tel: +49 941 9432471 E-Mail: neva.caliskan@helmholtz-hiri.de ...