Misfolding and aggregation can happen to any protein, but a specific group of proteins known as intrinsically disordered proteins (IDPs) are especially prone to forming amyloids. IDPs make up ...

A team that includes a RIKEN researcher has refined a lab test for measuring protein aggregate levels in samples from ...

Protein aggregation is the process by which misfolded proteins adopt a conformation that cause its polymerization into aggregates and organized fibrils. Many neurodegenerative diseases ...

Misfolded proteins (also called toxic conformations) are typically insoluble, and they tend to form long linear or fibrillar aggregates known as amyloid deposits. But how can a protein change so ...

Lurking within the genomes of nearly all species—including plants, fungi, and even humans—are genes that are passed from generation to generation with no clear benefit to the organism. Called "selfish ...

Protein aggregates can irreversibly form in solution through a number of processes and are common within unstable samples. This results in a lower concentration of non-aggregated materials which can ...

To overcome these limitations, scientists developed the real-time quaking-induced conversion (RT-QuIC) assay for both research and diagnostic use, where prion seeds taken from specimens induce protein ...

Scientists at Scripps Research developed a stable form of carnosic acid, which enhanced memory function and improved ...

Researchers have found that a chemical reaction links air pollution and Alzheimer's; blocking this reaction could be a ...

Lurking within the genomes of nearly all species—including plants, fungi, and even humans—are genes that are passed from ...