In an exclusive interview with PEOPLE, Jay and Pamela — both born with osteogenesis imperfecta, or brittle bone disease — open up about keeping a positive mindset despite challenges. They are starring ...

Osteogenesis imperfecta also has many types with varying levels of symptoms caused. It is important to know more about this ...

According to the Osteogenesis Imperfecta Foundation, the life expectancy of OI Type III varies. While some people with OI may live a normal lifespan, some pass away during childhood or adulthood ...

Osteogenesis imperfecta (OI), also known as brittle bone disease, is a rare genetic disease affecting the connective tissue and bones. In this disease, bones become extremely fragile and break or ...

Osteogenesis imperfecta (OI) is probably the most common genetic form of fracture predisposition. The term OI encompasses a broad range of clinical presentations that may be first apparent from ...

TLC star Pamela Chavez praised fiancé Jay Manuel for being a comforting partner and credited him for the positive impact he's ...