Identifying the unstable moieties can help guide the synthetic optimization of lead compounds. Identifying the CYP450 enzymes involved in the metabolism of lead compounds is important for predicting ...

Bioversys AG has announced that its BV500 NTM program has reached its second milestone with the identification of up to five optimized lead compounds, under the CF AMR Syndicate collaborative ...

“By starting from a much larger chemical space and transforming drug design to an optimization problem ... to discover novel lead compounds for a wide range of medical indications.

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support the discovery, synthesis, screening and optimization of small molecule ligands or lead compounds. The Center for ...