At subsequent 4-week intervals, the regimen was modified in patients with blood pressure >130/85 mm Hg: up-titration of olmesartan medoxomil to 40 mg/d; addition of hydrochlorothiazide 12.5 mg/d ...
A total of 2306 patients were enrolled in the initial open-label phase of the study. Of these, 627 patients who showed a suboptimal response after 8 weeks of treatment with olmesartan medoxomil 20 ...
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