mRNA splicing is a fundamental part of the process ... might be treated by repositioning the normal copy of the gene for that protein near nuclear speckles to boost splicing and restore healthy ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

"Incorrect splicing of REST mRNA can cause the resulting protein to ... allowing it to splice into its normal form. The researchers implanted neuroendocrine cancer cells under the skin of lab ...

Splicing does more than it was initially cut ... During translation of normal mRNA, Y14 (located upstream of exon–exon junctions) would be removed. As the termination codon of higher eukaryotes ...

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

but a new study shows that trans-splicing of mRNAs can be a frequent and regulated occurrence in some normal cells. The levels of the chimeric mRNA oscillated with the menstrual cycle in a ...

Cambridge, Massachusetts-based Envisagenics focuses on using AI to analyse errors in RNA splicing, a process in which a precursor form of messenger RNA (mRNA) – which is used as a template for ...