Neural tube defects arise when the neural tube does not close completely by the 29th day after ... this closure does not occur, and gives rise to neural tube defects. The most common forms of NTDs ...

Neural tube defects are abnormalities that affect the brain, ... When the closure defect is lower down in the neural tube, it gives rise to a condition commonly referred to as spina bifida.

Failure of neural tube closure leads to neural tube defects, such as spina bifida and anencephaly, and has been linked to insufficiency of folate. The genetic and molecular mechanisms that link ...

"A defect in the mLin41 gene doesn't allow the tube to close because not enough neural progenitor cells are being made." The study was the cover story this week in the journal Genes & Development.

But the estimated risk was substantially attenuated at red blood cell folate concentrations above 1,000 nmol/L. For example, estimated neural tube defect risk was 6 per 10,000 births at a red ...

video: This is an annotated video of mouse neural tube closure. Animal studies are playing a larger role in understanding and treating human neural tube defects in utero and in newborns. This ...

Three presentations covered the embryology of neural tube defect (NTD). Dr. Muriel Harris described neural tube closure in the mouse. The mouse has three closure sites, with the site of closure 2 ...

Neural tube defects, including anencephaly and spina bifida, are caused by the incomplete closure or development of the spine and skull. The researchers also found evidence that the gene may be an ...

NTDs are severe congenital malformations that result from failure of neural tube closure by the 28th day of gestation. The neural tube forms the early brain and spine.

The estimated risk of a neural tube defect was highest at lower red blood cell folate concentrations (neural tube defect risk of 25.4 per 10,000 births at a red blood cell folate concentration of ...

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers ...

Birth defects research. Part A, Clinical and molecular teratology (ISSN: 1542-0752, 1542-0760) ...