Chemists use modified DNA nucleotides to create new materials. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 10 / 171011180157.htm. Scripps Research Institute.

LA JOLLA, CA - Oct. 11, 2017 - DNA evolved to store genetic information, but in principle this special, chain-like molecule can also be adapted to make new materials. Chemists at The Scripps ...

Modified nucleotides like m5C in saRNA enhance vaccine efficacy, stability, and reduce inflammation, offering a promising approach for SARS-CoV-2 protection.

Biotinylated nucleotides have emerged as a powerful tool in molecular biology, enabling researchers to explore genetic materials with unprecedented precision and sensitivity. These modified ...

In a Perspective, researchers propose that modified nucleobases, ... Article #18-09041: "Modified nucleotides may have enhanced early RNA catalysis," by Steven K. Wolk et al.

These cells incorporate chemically modified nucleosides into their DNA, which is toxic to them. The findings indicate that it might be possible to use modified nucleotides for specific killing of ...

“Their fundamental work in using modified nucleotides, the building blocks of RNA, to avoid activation of the innate immune system will be key to the successful use of future RNA vaccines and ...

Nucleotides consist of a five-carbon sugar and a nitrogenous base (which together make up the nucleoside), and three phosphate groups. Cytosine is the most commonly modified base in DNA.

To carry out this method, the researchers feed cells modified nucleotides that contain a special alkyne group. During a burst of transcription, those modified nucleotides get incorporated into the ...

Crucially, they found that the enzymes that recycle nucleotides are highly specific. They don't use the modified nucleosides, so the new DNA is epigenetically 'clean.' ...