RNA-based therapeutics are gaining traction due to advancements in delivery technologies, despite historical challenges with ...

Psychiatric disorders challenge us deeply. At the University of Arizona, researchers dissect their molecular roots, focusing ...

Since a miRNA may regulate many of its targets at the translational level without affecting mRNA abundance, proteomic methods are best suited for revealing the full spectrum of miRNA targets.

The mRNA targets of miRNA can be determined by using bioinformatics methods and bioassays for monitoring the amounts of target mRNA. In plants, miRNA binding sites are usually found in the coding ...

The kit purifies all sizes of RNA, from large mRNA and ribosomal RNA down to microRNA (miRNA). The RNA is preferentially purified from other cellular components such as proteins, without the use ...

"It is striking that in both mice and humans, the same miRNA binds in two places on the SRL mRNA,", said Marzluff, ...

Future research directions include developing drugs or antibodies targeting specific METTL family members and exploring the use of nanomaterials to deliver miRNA corresponding to METTL family mRNA.