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Nearly 70% of the drugs currently being developed target membrane receptors. Located outside the cell, these receptors play a decisive role in transmitting information to the inside of the cell.
Prof. Maruyama suggests that rotation of a receptor's transmembrane region requires less energy than lateral movement of monomeric receptors inside the fluid membrane proposed by the "dimerization ...
The ability to selectively generate a bioluminescent signal when the membrane receptor is in the early endosome to monitor receptor internalization (i.e., membrane trafficking) is novel." ...
AMPA Receptors On Cell Membrane Make Us Smarter Date: September 15, 2009 Source: NWO (Netherlands Organization for Scientific Research) Summary: AMPA receptors are an important regulating factor ...
The multifaceted biology of membrane proteins is illustrated with the example of seven-transmembrane-domain receptors. The receptor interacts with various receptor activity modifying proteins ...
Porcine reproductive and respiratory syndrome virus (PRRSV) continues to devastate the global swine industry, yet the ...
A research team with members from Monash University, the ARC Centre for Cryo-electron Microscopy of Membrane Proteins, the University of Tokyo and the University of Otago have determined the shape ...
GPCRs (G-protein-coupled receptors) represent the largest family of membrane receptors currently targeted by approved drugs. It is estimated that approximately 700 approved drugs target GPCRs ...
Receptor clustering within the membrane. Porphyrin amphiphile 1 is ideally suited as a minimalist membrane-anchored receptor ().Cholesteryl moieties are used extensively as lipid-membrane anchors ...
Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. M. Razandi, A. Pedram, G.L. Greene, E.R.
Nearly 70% of the drugs currently being developed target membrane receptors. Located outside the cell, these receptors play a decisive role in transmitting information to the inside of the cell.
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