BOSTON - Mass General Brigham, the largest health care system in Massachusetts, announced layoffs Monday that will affect hundreds of workers, citing a $250 million projected budget gap. The layoffs will be "focused on non-clinical and non-patient facing roles,

Mass General Brigham attributed the layoffs to an expected budget shortfall of $250 billion over the next two years.

Facing rising costs and hoping to make its sprawling network more efficient, the state’s largest private employer aims to cut payroll costs by over $200 million.