When we shot CSI: Miami, Ryan was written as ambitious and a little impetuous. I think Damon may have been that at one point in his career, but he’s gotten older and wiser and mellowed out a bit.

CSI: Miami became Caruso's defining project, with Caine being his most recognizable role. Perhaps sensing it would be his acting legacy, Caruso retired from acting after CSI: Miami ended in 2012.