Mammary organoids derived from mouse embryonic stem cells could offer clues into mammary gland developmental origins and help researchers study breast cancer. Sneha Khedkar is an Assistant Editor at ...

Estrogen and progesterone promote the proliferation and activity of mouse mammary stem cells, according to new research published online today (April 11) at Nature-- possibly explaining the link ...

we study the communication between stem cells and their niche (e.g. neighbor cells, ECM) in multiple tissues including the intestine, mammary, skeletal muscle, and the hematopoietic system. Pekka is a ...

Specifically we have been interested in characterizing the role of Wnt and Fgf family members in normal mammary gland development and stem cell self-renewal, and the properties of tumor initiating ...

We have established variety of three-dimensional culture systems for mammary primary and stem cell-based organoids as well as patient tumor-derived explants for ex vivo target validation and for ...