Scientists suggest understanding ecDNA’s role in pancreatic cancer could potentially guide future strategies for making ...

Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to ...

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%. This poor prognosis stems from both late detection and the cancer’s notorious capacity to adapt and ...

That's because mis-regulation of Myc proteins is a hallmark of cancer and N-Myc plays a key role in childhood brain cancers. "Because Aurora-A stabilizes N-Myc against degradation, inhibiting the ...

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma—the most common ...

Both conditions stem from complex, interconnected biological processes, and one protein seems to play a central role: c-Myc, also known as Myc for short. This protein controls many essential processes ...

Canadian researchers have developed an effective new technique for identifying aggressive medulloblastoma-the most common type of malignant brain tumour in children-and potentially sparing young ...

Brukinsa plus R-CHOP demonstrated high efficacy and durable responses in double-expressor lymphoma, with manageable safety, supporting further phase 3 trials.

In healthy cells, a protein called MYC helps guide the process of transcription, in which genetic information is converted from DNA into RNA. But when cells turn cancerous, they start to produce way ...