correlated well with the prediction from MAP POD affinities that HSD would be a difficult target. Indeed, follow-up lead optimization efforts from HTS against HSD did not find any drug-like leads ...

strategic decision making with respect to drug discovery project management, from the initial steps in therapeutic target identification to ligand generation and the ensuing lead-optimization ...

Results from a new study published in Clinical and Translational Immunology found that dual-target antibody therapy can enhance cancer-fighting T cells more effectively than current single-target ...