correlated well with the prediction from MAP POD affinities that HSD would be a difficult target. Indeed, follow-up lead optimization efforts from HTS against HSD did not find any drug-like leads ...

strategic decision making with respect to drug discovery project management, from the initial steps in therapeutic target identification to ligand generation and the ensuing lead-optimization ...

This article explores methods to enhance efficiency in the drug discovery and development pipeline, focusing on optimizing processes and exploring innovations that could streamline the path from ...