New therapeutic possibilities for various diseases are made possible via mRNA. The adaptability of in vitro transcribed (IVT) mRNA is largely due to its simpler cell-free manufacture, cell cycle ...

As the first step in many workflows, in vitro transcription (IVT) has quickly emerged as an essential part of successful mRNA therapeutic manufacturing processes, optimizing and accelerating ...

The importance of in vitro transcription as a component of the mRNA therapeutic manufacturing workflow has grown significantly in recent years. The in-process raw materials for synthetic mRNA ...

Enter Primrose Bio with its offering of commercially available, proprietary, best-in-class RNA polymerases for mRNA synthesis by in vitro transcription (IVT) (Fig. 1). Primrose Bio’s Prima ...

Caption Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered ...

One way to produce the RNAs required for these new vaccines and therapeutics is in vitro transcription (IVT). When producing any IVT RNA, quality control of the RNA is essential to ensure that the ...

Pivot to U.S.-based Supply Chain for Critical Input Materials Completed - STONY BROOK, NY / ACCESS Newswire / April 21, 2025 / Applied DNA ...

Southern RNA is an Australian CDMO specialising in producing nucleic acid products that support the clinical development of ...